Contributor: Gordon K. Klintworth
Matthew-Wood syndrome (MIM 601186) is a rare syndrome in which microphthalmia is associated with hypoplasia or agenesis of the lungs.  It may also be accompanied by congenital heart disease, a diaphragmatic malformation, duodenal stenosis, pancreatic malformations and intrauterine growth retardation. Some cases result from truncating mutations in the STRA6 gene.