Contributor: Gordon K. Klintworth|
Familial partial lipodystrophy type 3 (familial partial lipodystrophy associated with PPARG mutations, OMIM #604367) is a variety of partial lipodystrophy [lipodystrophy - partial] caused by a mutation in PPARG. Aside from the lipodystrophy it is manifest by insulin-resistant diabetes mellitus [diabetes mellitus - resistant], hypertriglyceridemia, acanthosis nigrans, hypertension, and hirsutism. It differs from familial partial lipodystrophy type 1 [lipodystrophy - familial partial type 1] and familial partial lipodystrophy type 2 [lipodystrophy - familial partial type 2].