Contributor: Gordon K. Klintworth
The intradermal nevus is type of nevocellular nevus [nevus - nevocellular]. In contrast to junctional nevus [nevus - junctional] and compound nevus [nevus - compound], the intradermal nevus has little if any malignant potential. Only the dermis contains clusters of nevus cells; some of which are often multinucleated. When present melanin tends to be mainly in the most superficial cells. The presence of hairs on an elevated pigmented nodule usually signifies an intradermal nevus. Occasionally an obstructed hair follicle within a nevus ruptures eliciting an inflammatory response and an enlragement of the nevus. When this occurs concern about malignant transformation may occur. A variant of the intradermal nevocellular nevus is the neural nevus [nevus - neural].