Contribitor: Gordon K. Klintworth
Angioleiomyoma (angiomyoma, vascular leiomyoma) is a benign relatively common neoplasm that is found most often in the subcutaneous tissue of the lower extremities. The tumor is typically small and painful and affects women more often than men. Sharply demarcated nodules are composed of smooth muscle and numerous blood vessels with thick walls that resemble arteries, but without an elastic lamina. The tumor is believed to arise from vascular smooth muscle. The tumor may become hyalinized or undergo calcification.