Disease
Ehlers-Danlos syndrome type II
Overview

Contributor: Gordon K. Klintworth
Ehlers-Danlos syndrome type II (EDS 2, EDSII, Ehlers-Danlos syndrome mitis type, OMIM # 13010) is a mild form of  Ehlers-Danlos syndrome. It  is probably the commonest variant of this heterogeneous inherited syndrome that is manifest by hyperelasticity, joint hypermobility, tissue fragility, a hemorrhagic diathesis and bladder diverticula [diverticulum - bladder]. Mutations in the  COL5A1 or COL5A2 gene cause this type of Ehlers-Danlos syndrome, which is allelic with Ehlers-Danlos syndrome type I.