Contributor: Gordon K. Klintworth
Hypercalcemia has numerous causes including hyperparathyroidism from a parathyroid adenoma [adenoma - parathyroid gland], parathyroid hyperplasia [hyperplasia - parathyroid gland] or parathyroid carcinoma [carcinoma - parathyroid gland]. It can also result from end-stage chronic renal disease [renal disease], hypervitaminosis D, sarcoidosis, hypophosphatasia, the milk-alkali syndrome, Alport syndrome, multiple myeloma, metastatic carcinoma to bone [carcinoma - metastatic] and cancer-related hypercalcemia [hypercalcemia - cancer related]. In hypercalcemia calcium can deposit in the cornea and conjunctiva.