Contributor: Gordon K. Klintworth
A deletion of an entire chromosome or part of a chromosome is associated with several distinct syndromes or neoplasms. Syndomes [Wolf-Hirschorn syndrome, WAGR syndrome] associated with deletions of  some chromosomes have been identified. They involve chromosome 4 [chromosome 4 - deletion short arm], chromosome 5 [chromosome 5 - deletion long arm], chromosome 7 [chromosome 7 - deletion long arm],  chromosome 9 [chromosome 9 - deletion short arm], chromosome 11 [chromosome 11 - deletion short arm], chromosome 13 [chromosome 13 - deletion short arm, chromosome 13 - deletion long arm], chromosome 17 [chromosome 17 - deletion short arm],  chromosome 18[chromosome 18 - deletion short arm, chromosome 18 - deletion short arm], chromosome 22 [chromosome 22 - deletion long arm]. Patients with the Wilms Tumor-Aniridia-Gonadoblastoma-Retardation syndrome have a deletion of the short arm of chromosome 11. These individuals have aniridia and Wilms tumor. Rhabdoid tumor is associated with a deletion of part of chromosome 22 (22q11).