Contributors: Diva R. Salomão and R. Jean Campbell
The term chondrosarcoma refers to a malignant mesenchymal neoplasm characterized by cartilaginous differentiation. Several types of chondrosarcoma are recognized: classic chondrosarcoma (conventional chondrosarcoma) [chondrosarcoma - conventional], dedifferentiated chondrosarcoma [chondrosarcoma - dedifferentiated], clear cell chondrosarcoma [chondrosarcoma - clear cell], mesenchymal chondrosarcoma and malignant chondroblastoma. Chondrosarcoma may arise from a benign pre-existing lesion in cartilage such as an enchondroma of Ollier syndrome.